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CBD Up Close

CBD Up Close

Cutting through the CBD hype

Search Results for: antioxidant

Did you know that the US Government Holds the Patent to Cannabinoids as Antioxidants and Neuroprotectants?

May 28, 2019 by Travis Lindsay Leave a Comment

It’s true! The US Department of Health and Human Services owns the patent to Cannabinoids as antioxidants and neuroprotectants.

Not sure what that means? Here’s the abstract:

Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and HIV dementia. Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention. A particular disclosed class of cannabinoids useful as neuroprotective antioxidants is formula (I) wherein the R group is independently selected from the group consisting of H, CH3, and COCH3.

And here’s a study to go along with that along with the abstract reproduced below:

The neuroprotective actions of cannabidiol and other cannabinoids were examined in rat cortical neuron cultures exposed to toxic levels of the excitatory neurotransmitter glutamate. Glutamate toxicity was reduced by both cannabidiol, a nonpsychoactive constituent of marijuana, and the psychotropic cannabinoid (−)Δ9-tetrahydrocannabinol (THC). Cannabinoids protected equally well against neurotoxicity mediated by N-methyl-d-aspartate receptors, 2-amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic acid receptors, or kainate receptors. N-methyl-d-aspartate receptor-induced toxicity has been shown to be calcium dependent; this study demonstrates that 2-amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic acid/kainate receptor-type neurotoxicity is also calcium-dependent, partly mediated by voltage sensitive calcium channels. The neuroprotection observed with cannabidiol and THC was unaffected by cannabinoid receptor antagonist, indicating it to be cannabinoid receptor independent. Previous studies have shown that glutamate toxicity may be prevented by antioxidants. Cannabidiol, THC and several synthetic cannabinoids all were demonstrated to be antioxidants by cyclic voltametry. Cannabidiol and THC also were shown to prevent hydroperoxide-induced oxidative damage as well as or better than other antioxidants in a chemical (Fenton reaction) system and neuronal cultures. Cannabidiol was more protective against glutamate neurotoxicity than either ascorbate or α-tocopherol, indicating it to be a potent antioxidant. These data also suggest that the naturally occurring, nonpsychotropic cannabinoid, cannabidiol, may be a potentially useful therapeutic agent for the treatment of oxidative neurological disorders such as cerebral ischemia.

Filed Under: CBD Basics Tagged With: CBD patent, US Patent CBD

What CBD Skin Care Products Can Do For You

June 10, 2019 by Travis Lindsay Leave a Comment

Just about everyone can have healthier, better looking skin and CBD skin care products may help. CBD has been found to have antioxidant and anti-inflammatory properties that can heal your skin and make it look more beautiful.

From today.com:

“‘We know [CBD is] a strong antioxidant…. [It] protects collagen and stops DNA damage and protects from sun damage,’ said Dr. Farris, who recently spoke about CBD at the American Academy of Dermatology’s annual meeting. ‘It also can act as an anti-inflammatory for people with rosacea, eczema or acne.'” Check out this list of the best cbd gummies for anxiety and sleep.

And Rachel Nazarian, a board-certified dermatologist, had this to say from an article in Yahoo! Lifestyle:

“‘I’ve actually used CBD oil for things like wound healing, burns, and itching — and that’s where the science does back it.’

“Nazarian says there is evidence that suggests CBD oil can be beneficial for those with acne or hyperpigmentation and scarring attributed to breakouts. ‘Given the fact that CBD is anti-inflammatory and acne is an inflammatory condition for many people, along with the fact that it down regulates the production of oil, I actually think somebody that suffers from acne would benefit from CBD oil,’ she says, adding that it can help heal up those post-breakout dark spots, too.”

The advice that CBD Up Close gives to people considering using CBD products, whether for skin care or something else, is that they are definitely worth a try. There are a growing number of people who are finding results from using CBD products and there are no none serious side affects from using CBD. And, like with any beauty regimen, you will need to experiment to see what works. It may cost a little bit of money but your skin is worth it. Check out these hemp gummies for mood and health support, as well as other positive attributes.

Here are a couple of the top rated CBD skin care products for you to try!

Manuka Honey Cream - CBD skin care products

Manuka Honey Cream contains hemp oil and can help with healing breakouts on your skin and as a moisturizer as well. 395 people have rated this product with the average rating being 4.4 stars out of five. This Manuka honey cream, which also contains soothing shea butter, coconut oil, and hemp seed oil, also comes with a money-back guarantee, which is always a nice safety when you’re buying a new product. Check out this product and read some reviews on Amazon.com.

Natural Cannabis Hemp Hot Cream - CBD skin care products

Natural Cannabis Hemp Hot Cream is made to help combat cellulite and reduce inflammation. After 158 customer reviews, this product has an average rating of 4.3 stars out of five. It has safe, natural ingredients, and is infused with pure hemp oil to help relax sore muscles and inflammation. Read more about this product and some reviews on Amazon.com. It may be just the product you are looking for and at $17, this hemp hot cream is not going to break the bank!

Filed Under: CBD Basics, CBD Products Tagged With: CBD anti-inflammation, CBD antioxidant, CBD skin care, CBD skin care products

A Brief CBD Beginner’s Guide

May 26, 2019 by Chris McCarthy Leave a Comment

In a recent video, Vox Media tries to explain what they call the “booming CBD craze.” The video provides an overview of what CBD is, where it stands in the marketplace and in the mind of the consumer, as well as where it stands in legal and regulatory terms.

The narrator brings up the point that CBD stands right at the intersection of three consumer trends: the $49 billion herbal supplement industry, the growing anxiety economy, and the almost overnight rise of a legal cannabis marketplace.

Exponential CBD Industry Growth

CBD sales have increased by pretty wild percentages year over year since 2014, when there was an estimated $90 million worth of sales. Compare that to the $535 million worth of CBD good sold in 2018. And by the year 2020, there are estimates that CBD products will rake in just under $2 billion for the industry.

This is what they call a growth industry. But for a product this popular, CBD is barely regulated and people don’t even really know much about what it is or what it is supposed to do.

What we Know about CBD

Cannabidiol (the scientific term for CBD oil) is one of the 110 chemicals in cannabis called cannabinoids. THC, or tetrahydrocannabinol, is a different chemical altogether, and it’s the one that causes the high associated with marijuana. CBD won’t get you high.

You can imbibe CBD in a few ways. You can inhale it as a vapor, apply it to your skin, but ingesting it as edible oil is one of the more popular ways people are getting their CBD fix, since CBD is naturally soluble in fat, which means it’s easy to add to edible products. This may help explain the apparent ubiquity of CBD products.

There is, however, no proof that CBD cures the ailments that people think it does. CBD does have antioxidant and anti-inflammatory properties that have been shown to treat psychosis, anxiety, movement disorders, multiple sclerosis, and epilepsy and seizures. The FDA recently approved Epidiolex, a CBD based epilepsy drug, but there is not enough research for CBD to be prescribed for joint pain, arthritis, anxiety, depression, lack of appetite, cancer, or any of the other myriad problems for which it is said to provide relief. We do not know a lot about how CBD affects the brain or what doses or delivery methods are most effective.

CBD as a Cure: Things to Look Out For

Forgoing traditional medicine for CBD could pose problems for people with serious illness. And CBD interactions with other drugs you are taking could be problematic as well.

Since they are almost completely unregulated, CBD products often don’t contain what they say they do. The product may not have the cannabinidol claimed on the label (either they have extremely small doses or sometimes none at all) and some of the products may actually also contain THC.

IS CBD Legal?

Depending on which state you live in, CBD may or may not be legal. However, on a federal level it is still technically illegal.

The Drug Enforcement Agency takes the position that CBD is federally illegal, but it will not go after anyone possessing it or using it. Still I wouldn’t go through an airport with CBD.

The World Health Organization, in December 2017, concluded that CBD poses “no public health problems.”

The World Anti-Doping Agency removed cannabidiol from its prohibited substances list.

The 2018 Farm Bill as it stands would legalize CBD and industrial hemp nationwide.

Where We Stand with CBD

The CBD industry is growing. Legality is all but assured. There are powerful entities backing the CBD and industrial hemp industries, we’ve seen signs that financial services companies are changing their tune when it comes to processing payments for cannabis-related products, and there is apparent political will to move the country toward an environment where CBD is completely legal. When this happens, businesses that are prepared will be in a great position to take advantage of this burgeoning market.

Filed Under: CBD Basics Tagged With: cannabidiol, cbd beginners guide, cbd laws, cbd products, industrial hemp, regulations

Three Top Rated CBD Products for Dog Pain and Anxiety

May 22, 2019 by Travis Lindsay Leave a Comment

If you have had a dog for any amount of time you have probably had to deal with the aches, pains, and anxiety of your best friend. It’s hard watching your doggo suffer but, fortunately, there are solutions to the problem. What follows are three products from Amazon that CBD Up Close has analyzed reviews of to pick the three top rated CBD products for dog pain and anxiety.

All of these products come with a money-back guarantee, which we find to be a great thing when you are trying a new product for your dog, since the costs of all we do for our furry friends can add up.

PetHonesty Hemp Hip & Joint Supplement for Dogs

PetHonesty Hemp Hip and Joint Supplement for Dogs

With 610 reviews as of writing, the 90 count jar of PetHonesty Hemp Mobility dog treats is only $38.99 on Amazon (really not a bad price for a 90 count jar). In addition to hemp oil, this product from PetHonesty also includes glucosamine and turmeric and contains no “wheat, GMOs, corn, soy, sugar, and preservatives.”

One of the most prominent benefits people are seeing from the use of these treats is with dog hip dysplasia, which, if you have a large breed dog, is a common condition that can become debilitating if not properly taken care of. This product is reported to help ease the pain and stress your dog may be suffering. It is designed to help with joint support, mobility, and may serve as an antioxidant. Check out the product at the link below, read a few reviews, and see if you think it’s an option for you and your pet.

Link to purchase PetHonesty Hemp Hip & Joint Supplement for Dogs

CeeBeeDoo Dog Treats with Hemp Oil for Pain Relief & Anxiety

This product from CeeBeeDoo has 174 customer reviews and has a rating of 4.6 stars — see all the reviews on this product on Amazon. It comes in 12, 16, and 32 ounce jars and multiple flavors, including: BBQ Kabob, Cheese Wraps, Beef and Rice, Chicken Balls, Doggy Bacon, Milk Bone, Steak Bites, Turkey Jerky, and Beef Wraps. With the many different flavors there is sure to be one that your dog will like. In fact, what am I saying, your dog is going to love ALL of these flavors. From the comments, the most cited reason for using these treats was to reduce dog anxiety and stress. So if you have a dog that seems to be stressed out or otherwise bothered, these treats might makes sense for you. See the product and all the reviews, which are usually pretty helpful, at the link below.

Link to purchase CeeBeeDoo Dog Treats with Hemp Oil for Pain Relief & Anxiety

PremiumCare Calming Treats for Dogs

PremiumCare Calming Treats for Dogs

PremiumCare Calming Treats for Dogs comes in a 120 count jar and claims to “reduce symptoms of anxiety such as excessive scratching, barking, chewing, licking and salivating.” This product received 518 customer reviews as of writing with an average score of 4.3 stars out of 5. From the comments, this product works well treating anxiety in dogs with one purchaser saying that this works better than the prescription medications that their veterinarian prescribed them for their dog’s anxiety issues. *One added benefit of this product is that they are duck flavored. Yum! Especially for dogs. So if your dog or pet suffers from stress or anxiety, definitely take a look at this product, read some reviews, and see if you want to give this one a try.

Link to purchase PremiumCare Calming Treats for Dogs

Filed Under: CBD Products Tagged With: CBD anxiety relief dogs, CBD dogs, CBD pain relief dogs, CBD products for dogs, CBD reduce anxiety in dogs, CBD reduce pain in dogs

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